To prepare for your cycle we recommend you make certain adjustments to your lifestyle. You should avoid smoking, reduce alcohol consumption and increase your intake of folic acid. Also during this time a sample of the husband or partner’s semen is examined to make sure it is suitable for IVF.
When you have been matched with a donor, you will be given the treatment schedule and a prescription for the necessary medication. An appointment will be arranged with the Nurse Coordinator to discuss the treatment plan, to ensure a clear understanding.
The preparation for ovum donation treatment involves the synchronization of the ovarian cycles of both the donor and the recipient. This ensures that the embryos are placed in the recipient’s womb at the optimal time for their implantation. The preparation of the recipient’s womb is achieved by the use of subcutaneous injections which make the ovaries inactive. This is known as “down regulation”. Many women requiring donor eggs do not menstruate and therefore will not need to use this medication.
Once down regulation has been achieved, hormone tablets, Estrofem or Estradial Valerate are given daily for two weeks before eggs are to be obtained. This hormone prepares the lining of the recipient’s womb to receive the embryos.
An ultrasound scan will be carried out on Day 8 and 11 following commencement of these tablets. This will allow the Doctor to assess the womb lining to ensure that it is the appropriate thickness for embryo transfer.
If the womb lining is satisfactory, an additional hormone, PROGESTERONE in oil, Intramuscular injection is commenced once daily, when directed. This hormone ensures that the lining of the womb is in the best possible condition for implantation of the embryos.